Pancreatic cancer doesn’t discriminate, and Canada’s healthcare system shouldn’t either.

As a family, we know families from smaller provinces hit barriers at every turn, from accessing crucial tools like somatic testing to joining clinical trials that improve outcomes.

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Stories that move, insights that inform, and voices that advocate for change—our video collection captures the heart and mission of The Heather Cutler Foundation. From heartfelt tributes to critical discussions on cancer care reform, each video brings our journey to life, honoring Heather’s legacy and amplifying our call for better pancreatic cancer care across Canada. Watch, learn, and join us in turning advocacy into action.

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A pancreas travels the globe, showcasing the global effort to raise awareness for World Pancreatic Cancer Day on November 21

As this years generous, drawn-out Canadian summer winds down and the crisp air of autumn overtakes the summer vibes, a quieter season begins. With it comes not just an important month, but an important day to mark on our calendars: November 21, World Pancreatic Cancer Day.

World Pancreatic Cancer Day actually takes place within the wider World Pancreatic Cancer Awareness Month which runs the entirety of November each year and aims to shine a light on pancreatic cancer through a host of online and in-person events and some of the tough realities this disease brings.

When we first began researching the origins of World Pancreatic Cancer Day and looking into events, we realized there was so much more to discover about the incredible work of the World Pancreatic Cancer Coalition. Fast forward to today, and we are beyond grateful to share that we are now officially members of this powerful global network!

Events and Activities in Canada and Around the Globe 🌎

We took the liberty of doing a little researching as we were curious how events will vary across different countries around the world and organized some of the top events around the globe in November.


🌍 Global: The World Pancreatic Cancer Coalition is again this year holding their campaign ”Hello Pancreas” and annual virtual event. Participants are encouraged to blow up the hashtag #HelloPancreas and visit hellopancreas.com (which currently just redirects to their homepage at the time of writing) for more info. Registration: Register for the virtual event on Facebook.

🇺🇸 United States

Graphic with Ryan Moniz, Madison Marsh (Miss America 2024), Julie M. Fleshman, William Fisher, Anna Berkenblit, and G. Paris Johnson.
Join these experts, advocates, and survivors on World Pancreatic Cancer Day for a discussion on early detection and its impact on pancreatic cancer.

PanCAN Webinar: Early Detection and Pancreatic Cancer

Join PanCAN on World Pancreatic Cancer Day for a virtual panel discussion on early detection, featuring Miss America 2024 Madison Marsh, a dedicated advocate for pancreatic cancer awareness. Hosted by PanCAN President and CEO Julie Fleshman, JD, MBA, the event will explore the importance of recognizing symptoms, managing risks, and new research developments, including artificial intelligence and the Early Detection Initiative.

📅 Registration: RSVP here

Pancreatic Cancer Awareness Month Turkey Trot by Project Purple is Scheduled for Thanksgiving Weekend (November 28 – December 1), this virtual 5k run or 1-mile walk invites participants to join from their local neighbourhoods or treadmills, fostering a global movement against pancreatic cancer.

Register on Race Roster.

❄️ Cold Plunge For Pancreatic Cancer
Project Purple is hosting its first-ever cold plunge event on World Pancreatic Cancer Day. Join for an education session with Lauren and the Ice Cold Club on the benefits of cold plunging, followed by guided breathing exercises and a group cold plunge.

Registration: Sign up here!

🇨🇦 Canada

Walk for Hope – Fundraising and awareness walk organized by Pancreatic Cancer Canada, part of the national WPCC campaign. Location: Toronto, ON.

🥾Kicking Pancreas™ 5K - Craig’s Cause is hosting a virtual evening run/walk for all abilities and ages. Complete it anytime in November while wearing purple and glow-in-the-dark items. Registration: Sign up on Raceroster

Purple Kitchen Cooking Challenge – A cooking challenge with top chefs raising funds and awareness for pancreatic cancer research, live-streamed globally. Location: Vancouver, BC.

Landmarks in cities across Canada will be lighting up purple in solidarity with the cause so be sure to check with yours! Check out the finder provided by Pancreatic Cancer Canada below to see what‘s lighting up close to you.

PANCREATIC CANCER AWARENESS MONTH - Pancreatic Cancer Canada
On World Pancreatic Cancer Day and throughout November, we demand survival, not sympathy for those facing the world’s toughest cancer.

🇬🇧 U.K.

Purple Lights Campaign – Iconic buildings will be lit in purple to honor World Pancreatic Cancer Day and raise awareness. Join in and register to light up your home purple! Registration: Head over to Purple Lights UK

World Pancreatic Cancer Day - Webinar by Pancreatic Cancer Programme Join a panel of experts for a discussion on cancer-associated cachexia, covering research, clinical insights, and day-to-day management. Register on Eventbrite.

Pancreatic Cancer Action Fundraiser Gala – Gala dinner and fundraising event hosted by Pancreatic Cancer Action for WPCC. Location: London, U.K.

🇦🇺 Australia

Purple Lights for Pancreatic Cancer – Landmarks across Australia will be lit in purple to commemorate World Pancreatic Cancer Day. Location: Sydney, Melbourne.

🍽️ Fundraising Dinner for Pancreatic Cancer
Team Lopez is hosting a dinner event on World Pancreatic Cancer Day to raise awareness and funds for pancreatic cancer research. Join for an evening of food, drinks, and entertainment while supporting a crucial cause. Registration: Purchase tickets on Eventbrite!

🇩🇪 Germany: Purple Stride Run/Walk – A 5k run/walk event supporting pancreatic cancer research in Germany as part of a larger European WPCC initiative. Location: Berlin.

🌍 Global (Virtual): Virtual Fundraising Webinars – Educational webinars with survivors, doctors, and researchers sharing advancements in pancreatic cancer treatment. Location: Virtual.

🇯🇵 Japan: Mie University Purple Ribbon Event – Mie University Hospital hosts seminars, testimonials, and free consultations for early detection and dietary advice. Location: Mie University Hospital, Japan. PanCAN Japan PurpleStride Event – Annual PurpleStride walk in Tokyo to raise awareness and funds for pancreatic cancer research. Location: Shiba Park, Tokyo, Japan.

🇹🇼 Taiwan: Pancreatic Cancer Awareness Seminar – Public seminar by oncologists to raise awareness about pancreatic cancer symptoms and treatment. Location: Taipei Medical University, Taiwan.

🇨🇳 China: Public Awareness Campaign – Hospitals in Beijing and Shanghai hold talks, consultations with specialists, and seminars on pancreatic cancer treatment. Location: Beijing Union Medical College Hospital, China.

Unlike holidays such as Christmas or Valentine's Day, this day may pass unnoticed by many. But for Canadians touched by pancreatic cancer—whether through personal experience or the journey of a loved one—this day carries deep meaning. It's a moment to pause, reflect, and raise our voices in unity.

We’re Seeing PURPLE: Which Landmark did it best? 🗽

Every year in Canada, from the bustling cities of Vancouver and Toronto, to our very own Confederation Building in St. John’s, Newfoundland— businesses and organizations and government landmarks have illuminated that beautiful tone of purple to show they stand with our PC people. But it’s not just huge corporations that are pulling out the stops.

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The Late Alex Trebek Introduces World Pancreatic Cancer Day after being diagnosed with Pancreatic Cancer in 2020. His battle ended some twenty months later which is far more than some patients get.

Bringing Out the Star Power 🌟

Our mother, Heather was a long-time fan of Jeopardy and of course, Alex Trebek. And she was proud of her winning streaks. But Mr. Trebek isn’t the only star who has put their fame to work.

Notable celebrity attendants have included the hilarious Mindy Kaling, whose mother passed away from PC in 2012. ”Out Tonight”’s Rosario Dawson, Star Trek cast members Jonathan Frakes and Armin Shimerman. And most recently, the amazing Miss America, Madison March, who wasted no time in putting her spotlight to use.

Join us in uncovering the importance of World Pancreatic Cancer Day and the worldwide events and efforts dedicated to raising awareness for this vital cause.

History of World Pancreatic Cancer Day

World Pancreatic Cancer Day actually takes place within World Pancreatic Cancer Awareness Month which runs the entirety of November each year since 2000 . The first inaugural observance took place on November 13th, 2014. Thanks to the collaborative efforts of numerous Cancer organizations, notably the World Pancreatic Cancer Coalition (WPCC) observance and awareness of the event has flourished.

A promotional event post from the inaugural observance in 2014.

Fast-forward to ten years later and it’s currently observed in over thirty-five countries and counting across six continents. A historical search of Google keyword data for World Pancreatic Cancer Day however, shows the first usage in January of 2014 well before the November observance.

Participating organizations are collectively a part of the World Pancreatic Cancer Coalition (WPCC). Membership in the organization includes prominent figures of well-established national organizations in each participating country, such as Stefanie Condon-Oldreive, founder of Craig’s Cause.

How To Get Involved

World Pancreatic Cancer Day is all about both individuals and organizations coming together and participating in activities that shine some much needed spotlight on Pancreatic Cancer.

Canadian Events and Activities

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Sharing Personal Stories and Experiences

On World Pancreatic Cancer Day, sharing personal stories and experiences plays a crucial role not just in raising awareness but making Pancreayic cancer relateable. Each story represents a unique journey, filled with emotional highs and lows, moments of hope, and the reality of living with pancreatic cancer. By opening up about their experiences, patients, survivors, and families can shed light on the challenges they’ve faced, whether it’s navigating a complicated healthcare system, advocating for timely treatment, or grappling with the emotional toll of a diagnosis. These stories can inspire others to keep fighting and understand that they are not alone.

In addition to providing comfort and solidarity, sharing your personal experiences helps bring much-needed attention to the gaps in pancreatic cancer care, such as the limited access to clinical trials, delays in treatment, and the need for better support networks. When individuals and families share their struggles, they humanize this disease, showing that behind every statistic is a real person with real challenges. These stories become powerful advocacy tools, urging governments, healthcare providers, and the public to act. On World Pancreatic Cancer Day, these personal narratives help build a community that pushes for better treatment, increased research funding, and ultimately, improved survival rates for all patients.

Utilizing Downloadable Materials

If you‘re really looking to ace this assignment, you’ll be pleased to know Pancreatic Cancer organizations have done most the work for you and usually will have an array of materials to support you as you spread the word. Look for informative pamphlets, eye-catching posters or social media graphics to catch that head start, or, if you’re feeling creative try Canva or other tools to make something original.

Sharing really is caring, and these downloadables should inspire conversations about the disease, its symptoms, the importance of early detection and the critical need to increase its survival rates.

Consider hosting your own purple event, or a small gathering with family or friends; even just a single post about what you‘ve learned can elevate those conversations about pancreatic cancer and really drive home the importance of research funding and awareness.

What the Heather Cutler Foundation Is Doing

World Pancreatic Cancer Day With Team Heather
Join us online on World Pancreatic Cancer Day to support the same access to treatments, trials and care for every Canadian.

As the Heather Cutler Foundation evolves, we’re always looking for new ways to make a difference and drive change for better outcomes. We’ve learned that raising awareness alone isn’t enough; we need to take actionable steps. This means rallying policymakers, influencers, and everyday individuals to drive meaningful change.

Sign the Petition
Mandate National Guidelines for Pancreatic Cancer Testing and Treatment in Canada

With that said, we’re excited to announce a significant step that we’re taking towards that goal. On World Pancreatic Cancer Day, November 21, we will be directing our petition to the House of Commons.

😮
We did it! Our petition (e-5186) is currently supported and awaiting authorization by Health minister, Mark Holland for publication.

It’s the perfect occasion to advocate for a national framework that includes both somatic and genetic testing for pancreatic cancer. We believe this framework is crucial for effective and tailored treatments. Studies show that molecular profiling can lead to better outcomes and improved survival rates (ASCO, 2021; NCI, 2022).

In contrast to the U.S., where the FDA has streamlined regulations to support advanced testing and new biomarkers, Canada’s progress has been slower. In 2018, the United States had already crafted the Precision Medicine Initiative under the Obama administration to accommodate the rapidly evolving field of Molecular Profiling (Also referred to as Next-Generation Sequencing, Somatic Testing). Although changes are expected here in Canada between 2024 and 2026, patients here often face significant financial and logistical barriers to accessing these tests, often having to pay out of pocket or navigate a fragmented system (FDA, 2024; Health Canada, 2023).

We’re calling for a comprehensive national framework to ensure all Canadians with pancreatic cancer have access to genetic and somatic testing, supported by clear processes and funding. This will help bridge the gap between the U.S. and Canada in precision medicine and reduce the disparity in care.

Decision Makers

Mark Holland, Minister of Health

Mark Holland, appointed as Canada’s Minister of Health in July 2023, plays a pivotal role in shaping national health policies. With oversight of major agencies like Health Canada, the Public Health Agency of Canada, and the Patented Medicine Prices Review Board, he is directly involved in decisions that impact the accessibility and approval of new treatments. Given his responsibility for the Health Portfolio and its substantial budget, Holland is a key figure in addressing the treatment delays and healthcare disparities highlighted in our petition. His influence is critical in ensuring that Canadians receive timely and equitable access to essential medical care.

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Justin Trudeau

Prime Minister of Canada/Premier ministre du Canada

As Prime Minister, Justin Trudeau has significant influence over federal health policy and funding priorities. His support is critical for implementing national guidelines and increasing resources for pancreatic cancer care.

Wikipedia Page

Greg Fergus

Speaker, Canadian House of Commons

As Speaker of the House of Commons, Greg Fergus plays a crucial role in managing parliamentary proceedings and ensuring fair debate. His position allows him to bring attention to important issues like pancreatic cancer funding and research.

Wikipedia Page

Dominic Tan

Pan-Canadian Pharmaceutical Alliance (pCPA)

Dominic Tan is currently the acting CEO of the pan-Canadian Pharmaceutical Alliance (pCPA) and is responsible for heading up negotiations. He has been involved with the pCPA since its establishment and previously held the position of Senior Director of Negotiations and Outcomes.

Tracy Torchetti

Canadian Cancer Society

Dr. Stuart Edmonds

Canadian Cancer Society

As Executive VP of Mission, Research & Advocacy at the Canadian Cancer Society, Dr. Edmonds oversees cancer research funding and advocacy efforts. His support could help prioritize pancreatic cancer initiatives.

Kelly Masotti

Canadian Cancer Society

Understanding Pancreatic Cancer

Pancreatic cancer, of course, originates in the pancreas. When cells in the pancreas start growing uncontrollably, they form a tumour, which then eventually spreads to other parts of the body like the lymph nodes, liver, bones, duodenum or other parts of the body if not caught early.

Pancreatic Cancer is rarely diagnosed early because it often doesn’t show symptoms until it has progressed, mainly because of the lack of symptoms. But also because there are no approved early detection methods. In fact, almost (over 50%} of patients are diagnosed at later stages. (PANCAN, 2023)

Symptoms and Risk Factors

Pancreatic cancer is often referred to as a "silent" disease because it frequently does not cause any noticeable symptoms until the cancer has progressed to a more advanced stage where it’s more challenging to treat and options become more limited.

However, there are some signs and symptoms that individuals should be aware of and watch out for, even in the early stages of the disease: Jaundice, abdominal or back pain, unintentional weight loss, and digestive problems. (World Health Organization, 2022) 

While pancreatic cancer symptoms early in the game may be subtle or easy to overlook, being mindful of changes in your health and reporting anything that feels out of sorts to your healthcare provider can be crucial for early detection and improved outcomes.

Some key signs and symptoms of pancreatic cancer may include:

  • Jaundice: This condition causes a yellowing of the skin and eyes. It can be a sign that cancer is affecting the bile ducts. (Mayo Clinic, n.d.)
  • Pain in the Abdomen or Back: Persistent pain or discomfort in the stomach or back might indicate pancreatic issues.
  • Unintentional Weight Loss: Losing weight without a diet or exercise change might indicate an underlying problem.
  • Digestive Problems: Issues like nausea, vomiting, or loss of appetite could be related to pancreatic cancer.
  • Active Diabetes, especially long-term diabetes is associated with an increased risk.

Certain factors increase the likelihood of developing pancreatic cancer. Unfortunately, some of these factors are not something that we can change. Some we can. However, recognizing that they can elevate your risk can help with early detection. 

  • Age: The risk increases as you get older, with most cases occurring in people over 65.
  • Lifestyle Choices: Smoking is a significant risk factor. Quitting smoking can lower your risk.
  • Genetics: A family history of pancreatic cancer or certain genetic conditions can elevate your risk. Genetic counselling might be an option if you have a strong family history.
  • Chronic Pancreatitis: Long-term inflammation of the pancreas has been linked to an increased risk of cancer.
  • Body Weight: Maintaining a healthy weight can be a preventative measure. Obesity has been associated with a higher risk of developing pancreatic cancer.

Importance of Early Diagnosis

Early diagnosis is crucial in the fight against pancreatic cancer, as it significantly improves treatment outcomes and survival rates if caught at earlier stages when treatment options are much more effective.

Unfortunately, pancreatic cancer is often diagnosed at later stages due to its subtle and nonspecific early symptoms. Raising awareness about the importance of early detection is a key focus of World Pancreatic Cancer Day. Symptoms such as unexplained weight loss, abdominal pain, and jaundice should not be ignored. Regular check-ups and discussions with healthcare providers about risk factors, including family history and lifestyle choices, can lead to earlier detection. The Heather Cutler Foundation emphasizes the need for increased research into early detection methods and improved access to diagnostic tools like genetic and somatic testing. By promoting early diagnosis, we can potentially save more lives and improve the overall prognosis for those affected by pancreatic cancer.

Raising Awareness: Strategies and Tools

Social Media remains an invaluable tool for spreading information about Pancreatic Cancer and promoting awareness of World Pancreatic Cancer Day.

Social Media and Engagement

Every single person can play a crucial role in raising awareness for World Pancreatic Cancer Day and pancreatic cancer through social media engagement. One effective strategy is to share personal stories, whether you're a survivor, caregiver, or have been affected by the disease in any way. Using popular platforms like Facebook, Twitter, and Instagram, you can post informative content about pancreatic cancer symptoms, risk factors, and the importance of early detection.

The use of specific hashtags such as #WorldPancreaticCancerDay, #WPCD, or #DemandBetter are great for increasing visibility and helping everyone join the global conversation. Consider changing your profile picture or using a themed frame to show support for the cause. Sharing and commenting on posts from pancreatic cancer organizations can help amplify their message and reach a wider audience. You can also participate in or create social media challenges related to pancreatic cancer awareness, encouraging friends and family to get involved. By leveraging your social networks, you can help educate others about this disease and potentially save lives through increased awareness.

Educational Workshops and Webinars

Did Researchers Develop a Better Nerve Block? post image

With Pancreatic Cancer set to be the third leading diagnosed Cancer in Canada over the coming years, any studies that advance our ability to reduce pain, especially the severe abdominal pain associated with late-stage pancreatic cancer is an achievement in itself.

We’ve stressed the importance time and time again of early interventions in your journey with Pancreatic Cancer. That applies to so many potential treatment options- nerve block or palliative care—have those conversations early so you know what’s in your toolbox.

I remember the disappointment when my mother returned from her failed nerve block procedure after the tumour had blocked a clear path to the nerves.

Seeing how quickly the landscape of Pancreatic Cancer treatment changes in noting the amendment of US guidelines for pancreatic cancer treatment after this studies findings is reassuring knowing that we are making real progress towards better outcomes. We’ll be updating our database of treatment options to include this change here at Team Heather as well.

Understanding Pancreatic Cancer Pain

Although the direct cause is not fully understood, Pancreatic cancer frequently causes intense abdominal pain in its later stages when the tumor makes it‘s way closer to the bundle of nerves called the Celiac Plexus.

CT scan of the abdomen showing Pancreatic Cancer tumor near the Celiac Plexus which was later treated by nerve blockade.
Pancreatic cancer in computertomography. The patient suffered from back-pain and was treated successfully by Celiac Plexus Nerve Block. (Wikimedia Commons)

This pain often radiates to the back. According to Pancreatic Cancer Canada, this pain can be debilitating and significantly reduce a patient's quality of life. Existing pain management methods, like oral opioids or the Plexus Nerve Block, while effective, may have their own limitations or complications but generally both have a low side effect profile.

What exactly is this new alternative to the plexus nerve block?

This new radio-surgery treatment targets the celiac plexus nerve to alleviate pain presumably aggravated by the growth of the tumor. It’s a quick, outpatient procedure which means it can be done and you can go home the same day.

Key Findings from the Study

The study findings Celiac Plexus Radio-Surgery for Pain Management was conducted in Israel, Portugal, the United States, and, interestingly, right here in Canada at Princess Margaret Cancer Center and finished on November of 2022.

Durable Pain Reduction: The study found that over half (53%) of participants noticed a significant reduction in pain. However, as with any study that studies pain, we have to accept the limitations of how we quantify pain in that pain is very much a personal experience. What some may describe as uncomfortable pain, others may feel it’s unbearable.

Minimal Side Effects Profile: Quite similar to the traditional plexus nerve block, assuming there are no complications with the procedure, it maintains a minimal side effect profile. The most common complaints on the day of treatment are fatigue and nausea. Bear in mind that the side effects of any existing treatment will be more comprehensive and have been studied longer than any new treatment that is introduced.

Critical Eye 👁️

Introduces critical considerations for readers to maintain a balanced perspective on study findings. News outlets may prioritize marketing goals and cherry pick findings to attract audiences, rather then providing the full picture.

Quantifying Pain is difficult: Quantifying pain in any setting, let alone clinically, can be challenging as pain is a deeply personal experience, and different people may scale pain differently. Pain is quantified in clinical trials via the BPI Pain scale.

Patients still take existing opioid medications post-procedure: Participants in this trial were not required to halt the use of their existing opioid medications after the procedure. Although they were required to report the use of opioid medications post-procedure, this can create difficulty in quantifying the response to the procedure.

Minimal Side Effects Still Suck: While side effects can be reported as minimal, we have to bear in mind that even side effects like nausea or diarrhea, which some of us only experience once or twice, can minimize the reality of experiencing these side effects repetitively due to a medication (opioids) which provide needed pain relief.

The Role of Celiac Plexus Block in Pain Management

Celiac plexus block is a well-established technique for managing abdominal pain, particularly in pancreatic cancer patients. The celiac plexus is a network of nerves near the stomach, pancreas, and other abdominal organs. Traditional nerve block procedures involve injecting pain-relieving medication directly into this nerve cluster to interrupt the transmission of pain signals to the brain.

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Footage of a Celiac Plexus Nerve Block on a monitoring screen: (Video Credit: IRFacilities)

The effectiveness of celiac plexus block in reducing pain varies among individuals. The 30-60 minute procedure has a high success rate. According to PanCAN, the celiac plexus block can “relieve significant pain for up to 70% to 90% of patients.” The pain relief from this procedure typically lasts for several months and can be repeated if necessary.

However, not all patients are candidates for this procedure, mainly if the cancer has obstructed access to the nerve cluster, as was the case with my mother.

Comparing the Plexus Nerve Block to this New Treatment

Less Invasive: Both the existing nerve block and this new approach to treating pancreatic cancer pain can be performed as outpatient procedures. This means patients can have the procedure completed and go home the same day. This is a significant advantage as it reduces hospital stays and associated costs and allows patients to recover in the comfort of their own homes.

Fewer Side-Effects: The plexus nerve block side effect profile and that of this new method for managing the pain associated with Pancreatic Cancer are both on the smaller side without complications. This new approach does not introduce problems with low blood pressure as seen in nerve blocks, a common side effect due to the proximity of the celiac plexus to major blood vessels.

Longer Lasting Relief: According to PanCAN which states traditional plexus nerve blocks offer anywhere between three and six months of pain reduction—the new treatment has shown promise in providing longer-lasting relief. Participants in the trial reported significant pain reduction that extended beyond the typical duration seen with nerve blocks, highlighting the potential for this new method to offer more sustained pain management.

Reduced Opioid Dependence: Effective pain management through this radiosurgery approach can decrease the reliance on high doses of opioid medications that, while providing pain relief, come with a much more severe side effect profile that, while addressing one need by reducing pain, creates more problems. Reduced dependence on opioids means fewer side effects like constipation, nausea, and the risk of addiction, which can significantly improve patients’ quality of life.

Exploring other methods

According to John Hopkins, these methods made be used in addition to, or on their own.

Nerve Cutting Surgery: Thoracoscopic splanchnicectomy, surgeons cut out specific branches of the nerve bundle.

Guided Nerve Block: Radiologists are guided by a small camera as they enter through the stomach and inject pain medication into the nerves near the pancreas.

Benefits Beyond Pain Management

This new radiation therapy offers other significant benefits in addition to alleviating pain. It targets and attacks pancreatic cancer cells, making them vulnerable to the immune system. This dual approach not only provides pain relief but also contributes to the overall treatment of the cancer, potentially slowing disease progression and improving survival rates.

Who Benefits from Clinical Trials?

For patients with metastatic pancreatic cancer who can undergo traditional plexus nerve block, the procedure already has benefits, many of which improve quality of life, including an overall reduction in opioid use (pretty simple logic here, if we can reduce the pain using other methods, it reduces the need for opioids). Opioids are not a solution either; they often come with their side effect profile, which makes the side effects of these procedures seem like a walk in the park.

Illustration showing clinical trial toolset which research, notebook, and pills implying development of pancreatic cancer research.

Clinical trials play a crucial role in advancing cancer treatment and pain management. They provide patients access to cutting-edge therapies that are not yet widely available and contribute to the scientific understanding of how these treatments work. Participants in clinical trials also receive close monitoring and comprehensive care from a team of specialists, which can lead to better overall health outcomes.

Conclusion

The new treatment targets tumour cells to alleviate pain. It also aims to target and attack pancreatic cancer cells, making them vulnerable to the immune system. With the promising results from the study, including durable pain reduction and minimal side effects, this new form of radiation therapy represents a significant advancement in the management of pancreatic cancer pain.

By integrating these new insights and technological advancements into treatment plans, we move closer to offering pancreatic cancer patients relief from their pain and a tangible improvement in their overall prognosis and quality of life. The future of pancreatic cancer treatment looks brighter with each discovery.

What is this new treatment for people living with pancreatic cancer?

Researchers have developed a new kind of radiosurgery to help manage pain in pancreatic cancer patients. This treatment focuses on the celiac plexus nerve, which is responsible for transmitting pain signals from the abdomen, where the pancreas is located.

By using high doses of targeted radiation, this treatment can interrupt pain signals, offering relief that may last longer than other methods. Because it’s non-invasive (meaning no surgery or incisions), patients can often go home the same day, and it is performed on an outpatient basis. This approach provides an alternative for patients who might otherwise rely on regular procedures or high doses of medication to manage their pain.

How does the new treatment compare to the existing Celiac Plexus Nerve Block?

Existing celiac plexus nerve blocks typically involve injecting anesthetic or steroid medication directly into the celiac plexus nerve to block pain. While effective, these blocks tend to provide relief that lasts only a few months, meaning patients need to repeat the procedure frequently.

In contrast, this new radiosurgery treatment uses highly focused radiation to target the nerve, potentially offering pain relief that lasts longer than traditional injections.

This radiosurgery approach also comes with fewer risks of complications and may reduce the patient’s need for opioid painkillers, which can lead to dependency issues. This lasting effect and lower need for follow-up make it a promising option for long-term pain management.

What are the most common complications of celiac plexus block?

The most common complications are hypotension (low blood pressure), diarrhea, transient back pain. The pain may also temporarily worsen before it gets better. These symptoms usually go away on their own within a day or two.

Unlike opioid medications, which can cause long-term side effects such as drowsiness, constipation, and risk of addiction, this procedure’s side effects are short-lived and manageable. Because it is non-invasive, it avoids the risks associated with surgery, such as infection or prolonged recovery, making it a safer option for many patients.

Is this treatment available now for all pancreatic cancer patients?

At this time, the new radiosurgery treatment is still being tested in clinical trials and is available only at certain research hospitals or medical centers participating in these studies. These trials are ongoing in several countries, including Canada, so the treatment is not yet widely accessible. Not all patients may qualify for these trials, as each study has specific eligibility criteria, such as cancer stage and overall health.

Patients interested in this treatment are encouraged to talk to their healthcare providers about clinical trial options and whether this treatment could be right for them. If trials show positive results, this treatment could eventually become more widely available.

Does this new treatment affect cancer itself, or only the pain?

The main purpose of this new radiosurgery is to manage pain by targeting the nerves that transmit pain signals, not to treat the cancer itself.

However, there is some evidence to suggest that by helping patients feel better and experience less pain, this treatment can improve their overall quality of life and help them respond better to other cancer treatments. Some studies also suggest that pain management can support immune function by reducing stress on the body, which may be beneficial, although it does not replace traditional cancer therapies like chemotherapy.

The main focus, however, remains on making patients more comfortable and reducing their pain levels so they can better handle other aspects of their treatment and daily life